Antioxidants

Antioxidants are compounds in foods that have the ability to find and fight cell-damaging molecules called free radicals. Free radicals can do a lot of damage. They have the ability to alter your DNA, which can result in cancer or many other health challenges. They can harm the membranes of your cells, so they are unable to perform their assigned functions, and at high levels, they can result in oxidative stress, which can lead to the development of tissue damage and chronic diseases.

Antioxidants in aloe vera

Aloe vera contains scores of bioactive elements that provide various health benefits. In addition to amino acids, enzymes, proteins, carbohydrates, and lipids, the plant is rich in antioxidants. The food and cosmetic industries have used the antioxidants in aloe vera to enhance the nutritional value of food and extend the shelf life of beauty products. Experts are becoming increasingly aware of the value of these antioxidants, which are found in the plant’s leaves, gel, and flowers.

In a 2019 report in Plant Foods for Human Nutrition, the authors note the types of antioxidants in plants and one way to reap the most benefits from them. They note, for example, that the best time to harvest aloe vera leaves is after the plant has been growing for three years because the levels of a group of antioxidants known as flavonoids are highest then. Other antioxidants found in aloe vera include polyphenols (e.g., catechins, quercetin, rutin) and vitamins and minerals (e.g., vitamin C, beta-carotene, alpha-tocopherol, copper, zinc).

Read more about the health benefits of aloe vera

Benefits of antioxidants in aloe vera: research

In a study that looked at the antioxidant abilities of aloe leaf gel using ORAC (Oxygen Radical Absorbance Capacity, a lab test that determines the total antioxidant capacity of foods and other chemical substances), the authors reported that the gel “may show promise in alleviating symptoms associated with/or prevention of cardiovascular diseases, cancer, neurodegeneration, and diabetes.”

In another study, a group of researchers evaluated the activity of two compounds that showed antioxidant activity against superoxide and hydroxyl radicals, which are involved in developing many health conditions, including cardiovascular disease, chronic inflammation, dementia, and cancer.

According to a review of clinical trial results done by an independent research firm, Lily of the Desert Aloe enhanced with Aloesorb “significantly improves vitamin C absorption, immune function, oxidative stress levels, and detoxification.” Aloesorb is a high concentration of aloe polysaccharides that helps enhance the supplement's ability to support immune function, digestive health, and antioxidant absorption.

Read about aloe vera and the immune system

In a clinical trial, experts evaluated the use of Lily of the Desert Whole Leaf Aloe Juice enhanced with Aloesorb in 75 healthy adults. In this double-blind, placebo-controlled effort, the oxidative reduction potential (ORP) improved by 40 percent in the participants who took aloe vera versus those who took a placebo. Aloe vera users also showed an 11 percent reduction in toxins accumulation compared to controls. The results suggest that this aloe vera supplement can safely and significantly improve oxidative stress (which contributes to and causes disease), enhance immune function, and improve detoxification in healthy individuals.

Here is yet another benefit of aloe vera. In a study in Phytomedicine, experts evaluated the absorption of vitamin C (a water-soluble nutrient) and vitamin E (a fat-soluble nutrient) with aloe vera or without. The authors found that using either aloe vera whole leaf extract or inner fillet gel improves the absorption of both vitamins. They noted that aloe vera should be used as a complement to these supplements.

Bottom line

Aloe vera contains a variety of powerful antioxidants that have been shown to possess an ability to enhance and improve immune function, detoxification, and other benefits. If you are looking for a way to manage your health better and improve the antioxidant activity and potential in your body, then consider aloe vera gel or juice as a daily supplement.

Sources

Hęś M et al. Aloe vera (L.) Webb.: Natural sources of antioxidants – A review. Plant Foods for Human Nutrition 2019 Sep; 74(3):255-65.

Loots du T et al. Aloe ferox leaf gel phytochemical content, antioxidant capacity, and possible health benefits. Journal of Agricultural Food Chemistry 2007 Aug 22; 55(17):6891-96.

Montgomery M. Evaluating the safety and efficacy of immune enhancement, ORP (oxidation and reduction potential), and reduction of toxicity levels (nitrates) using Lily of the Desert Aloe Vera Whole Leaf Juice enhanced with Aloesorb. Fenestra Research Labs, 2008 Winter

Tully L. Lily of the Desert Aloe Juice clinical studies summary. 2022

Vinson JA et al. Effect of aloe vera preparation on the human bioavailability of vitamins C and E. Phytomedicine 2005 Nov; 12(10):760-65

Zhang X et al. Isolation, structure elucidation, antioxidative and immunomodulatory properties of two novel dihydrocoumarins from Aloe vera. Bioorganic & Medicinal Chemistry Letters 2006 Feb 15; 16(4):949-53.

The post Aloe Vera and Antioxidants appeared first on NaturallySavvy.com.

Eating for better brain health and function

Following a nutritious diet does more than fuel your body; it stokes and energizes your brain. If you don’t properly nourish your brain with certain essential nutrients, then you risk a decline in cognitive function and an increased risk for neurodegenerative disease. Before discussing the best supplements for better brain health and function, let’s look at diet.

Read about building better brain health naturally

A diet that was specially developed to promote brain health, support brain function, and help reduce the risk of developing dementia, including Alzheimer’s disease, is called the MIND diet. It stands for Mediterranean-DASH Intervention for Neurodegenerative Delay and takes components from two highly acclaimed diets—Mediterranean and DASH—that focus on enhancing brain health.

The MIND diet was voted 4^th best overall diet in 2023 by US News & World Report, while its “parents” were voted 1^st and 2^nd (Mediterranean and DASH, respectively) for 2023 and have consistently been in the top two for many years. Research shows that people who adopted a diet very close to the MIND diet had about a 53 percent lower risk of developing Alzheimer’s disease.

Even if you follow the MIND diet, adding supplements may boost the benefits. Let’s explore some nutrients available in supplements that can help with better brain health and function.

Supplements for better brain health and function

What supplements might you need to help enhance or fill in the gaps in your diet to support your brain health and function? Here are eight candidates that have research to back them up.

Aged garlic extract (AGE)

Aged garlic extract is a supplement produced by aging fresh organic garlic at room temperature in an aqueous ethanol solution for up to 20 months. The result is a highly bioavailable product that has undergone some significant changes. For example, the garlic becomes odor-free and is easily digestible. It also loses its harsh organosulfur compound known as allicin, which is transformed into mild substances called S-allylmercaptocystine (found only in AGE) and S-allylcysteine.

Research has shown that AGE has neuroprotective properties that work against neuroinflammation and neurodegeneration. Two active ingredients in AGE are SAC (S-allylcysteine), which is the most abundant component, and FruArg [(N-alpha-(1-deoxy-D-fructose-1yl)-L-arginine]. All three of these substances appear to work to improve brain health. FruArg can cross the blood-brain barrier, which “further supports its potential as a therapeutic compound.”

Read about aged garlic extract: AGE for a healthier you

Carnitine

Carnitine is an amino acid and nutrient that is found in food and is also produced by the body from two other amino acids, lysine and methionine. Its main role in the body is to help transport fatty acids into the mitochondria in cells, where they are burned for energy.

The standard biologically active form of carnitine is L-carnitine. However, several other forms, including acetyl-L-carnitine, may be the most beneficial form for the brain. Research shows that this form of carnitine “shows promise in the treatment of aging and neurodegenerative pathologies by slowing the progression of mental deterioration.”

Folic acid

Folic acid is the supplement form of folate, the natural type of B vitamin (B9) found in food. You need folic acid to develop RNA and DNA and to form neurotransmitters in the brain. Several B vitamins, especially folic acid, are involved in brain health and memory. Research has shown that a higher intake of folate/folic acid is associated with a significantly reduced incidence of dementia.

Ginkgo biloba

Ginkgo biloba has been around for millions of years, but recently, researchers uncovered its value for brain health and function. This herb is a powerful antioxidant that can improve blood circulation in the brain and help individuals living with mild cognitive impairment. In a 2023 systemic review that included nine clinical trials involving 946 patients, they found ginkgo to be beneficial for memory, attention, executive functioning, and processing speed. Significant improvement was also seen in anxiety and depression.

Lecithin

Lecithin is a naturally occurring fatty acid involved in metabolic function, energy balance, and the regeneration of brain cells. More specifically, lecithin is important for the production of the neurotransmitter acetylcholine. Healthy levels of this neurotransmitter are necessary to support healthy brain function.

Phosphatidylserine

Phosphatidylserine is a type of fat (phospholipid) that helps protect brain cells against damage and sends signals between them, which promotes memory and cognitive function. Levels of phosphatidylserine decline as you age, which is why some people take a supplement as they age.

Siberian ginseng

Despite its name, this herb is not true ginseng. However, Siberian ginseng (Eleuthero) is an adaptogen, which means it works to help balance and manage stress in the body. Among the potential benefits of this herb is the ability to increase blood flow, including to the brain, which may improve memory, concentration, and other mental functions.

Vitamin B12

This B vitamin plays several functions in brain health. Some research has shown that people with early-stage dementia who took vitamin B12 and omega-3 fatty acids had slowed mental decline. One study noted that low levels of vitamin B12 can impact memory performance. A 2020 study in Cureus noted that “Vitamin B12 deficiency is linked to cognition, and replacement therapy may be an option to improve patient cognition outcomes.”

Bottom line

Several natural nutrients and herbs, including memory and concentration, benefit brain health and function. Kyolic Brain Focus provides ginkgo biloba for sharpness, mental acuity, and attention. Kyolic Brain Memory combines aged garlic extract, ginkgo biloba, and Siberian ginseng for better concentration, learning, and recall. Kyolic Neuro-Logic is a special formula of aged garlic extract along with carnitine, choline (from lecithin), folic acid, ginkgo biloba, phosphatidylserine, and vitamin B12 for memory, learning, and mental acuity.

Sources

Aimera R. L-carnitine: benefits, side effects, sources, and dosage. Healthline 2023 May 9

Best diets 2023. US News & World Report 2023 Jan 3

Hort J et al. Ginkgo biloba extract EGb 761 in the treatment of patients with mild neurocognitive impairment: A systematic review. Neuropsychiatric Disease and Treatment 2023 Mar 23; 19:647-60.

Huizen J. 12 potential health benefits of eleuthero. Medical News Today 2023 Jul 12

Köbe T et al. Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment. American Journal of Clinical Nutrition 2016 Apr; 103(4):1045-54.

Ma X et al. Phosphatidylserine, inflammation, and central nervous system diseases. Frontiers in Aging Neuroscience 2022; 14:975176.

Mawer R, Ajmera R. L-carnitine: benefits, side effects, sources, and dosage. Healthline 2023 May 9

MIND diet. US News & World Report 2023 Jan

Morris MC et al. MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimer’s & Dementia 2015 Sep; 11(9):1007-14

Northrop A. Best brain supplements. Forbes 2023 Jun 9

Oulhaj A et al. Omega-3 fatty acid status enhances the prevention of cognitive decline by B vitamins in mild cognitive impairment. Journal of Alzheimers Disease 2016; 50(2):547-57.

Phosphatidylserine. Cleveland Clinic 2023 Jul 14

Sam C, Bordoni B. Physiology, acetylcholine. StatPearls 2023 Apr 10

Song H et al. Bioactive components from garlic on brain resiliency against neuroinflammation and neurodegeneration. Experimental and Therapeutic Medicine 2020 Feb; 19(2):1554-59.

Traina G. The neurobiology of acetyl-L-carnitine. Frontiers in Bioscience (Landmark Ed). 2016 Jun 1; 21(7):1314-29.

Virmani MA, Cirulli M. The role of L-carnitine in mitochondria, prevention of metabolic inflexibility and disease initiation. International Journal of Molecular Science 2022 Feb 28; 23(5):2717

Wang Z et al. B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis. Nutrition Reviews 2022 Mar 10; 80(4):931-49.

The post Supplements for Better Brain Health and Function appeared first on NaturallySavvy.com.

Why support your immune system

Why is supporting your immune system so critical? The past few years, in particular, have shown us that focusing on protecting and boosting immune system health needs to be a priority in our lives. The truth is we face challenges to the integrity of our immune system all the time, ranging from cold and flu germs to cigarette smoke, air pollution, parasites, mold, food additives, contaminants in personal care products, alcohol, poor nutrition, lack of sleep, chronic stress, and more.

Even if you follow a nutritious diet, exercise regularly, get sufficient sleep, and avoid as many immune system invaders as possible, it is still a challenge to keep your immune system operating at its best and to prevent health issues that can negatively impact your life. That’s why adding supplements to your other healthy lifestyle efforts is recommended.

Choosing immune system supplements

The array of immune system supplements on the market is vast, and choosing those that will most effectively help support immune function can be time-consuming. An essential starting point is to find supplements whose ingredients are effective in scientific research. Once that has been established, you will want to select those in a form you can take easily (tablet, capsule, powder, liquid) and are free of allergens, preservatives, and other additives.

Among the most researched and effective immune system supplements on the market are greens, aged garlic, and probiotics.

Greens for immune health

Greens have long been recognized as potent immune system supporters and among the healthiest vegetables. Dark leafy greens such as spinach, collards, beet greens, kale, mustard greens, and parsley, as well as grasses (wheat, barley), chlorella, spirulina, and kelp are among the members of this category. Their contributions to enhanced immune system function include vitamins A, C, K, and folate and the minerals calcium, zinc, potassium, and magnesium. The nutrients of dark leafy greens provide antioxidant powers from carotenoids, inflammation-fighting abilities, and plant-based nitrates, which may help fight hypertension and prevent heart disease.

In a 2022 article in Experimental and Molecular Medicine, the authors noted the significant contributions of chlorella to immune health in humans and animals. For example, scientists who gave chlorella supplements to healthy individuals found that the green significantly increased levels of certain cytokine factors, suggesting the immune-stimulating effect of chlorella.

Spirulina is another green that doesn’t always get much attention because people don’t serve it on dinner plates. However, this blue-green algae contains protein and immune system-supporting vitamins such as C, B6, and E. It also has been shown to stimulate the production of antibodies and help the immune system function more efficiently and effectively.

Are you eating at least 2 cups of dark leafy greens every day? That’s the recommendation, but if you are falling short or would like to boost your immune system, then Kyo Green® Harvest Blend powdered greens supplement can help you achieve your goal. Its unique formula of ancient grains, spirulina, and other greens and prebiotic fiber has been designed to support normal immune system function.

Aged garlic for immune health

Garlic is a well-studied and commonly used herb known for its immune-boosting abilities, antioxidant properties, and inflammation-fighting abilities. Although regular garlic has these qualities, they are enhanced in aged garlic extract (AGE). Kyolic AGE is made from a proprietary process that starts with organically grown garlic sliced and stored in stainless steel tanks at ambient temperature for up to 20 months. The chemical changes during this time enhance the antioxidants and phytochemicals in the garlic and make it more digestible while also killing off allicin, the compound in garlic responsible for its pungent smell.

Numerous studies have noted the immune system-boosting powers of aged garlic. In one clinical trial that involved 120 healthy participants, for example, the results suggested that the use of AGE enhanced the function of immune cells and reduced the severity of colds and flu. In a more recent clinical trial, the authors reported that “AGE, taken consistently, may be beneficial in preventing the development of chronic diseases associated with low-grade inflammation in adults with obesity.”

When shopping for an aged garlic extract supplement, look no further than Kyolic Immune Formula 103. In addition to organic aged garlic extract, it also contains other immune-boosting ingredients that support the benefits of garlic, such as vitamin C, medicinal mushrooms, astragalus, and olive leaf extract. The result is a bioavailable and odorless supplement that provides immune system support and is easy on the stomach.

Probiotics for immune health

Beneficial bacteria, aka probiotics, have been studied for various health benefits, including enhancement of immune function and digestive health. It’s well known that the integrity of your gut health is critical for optimal immune function and overall health. One way to bring balance to the microbiome in your gut is by providing it with probiotics consistently.

In a 2023 article in Cell, the authors explained that probiotic bacteria interact and stimulate immune cells and microflora and have “important health-promoting and immunomodulatory properties.” These beneficial bacteria “might represent a promising approach for improving immune system activities.” Although probiotics can be obtained from foods such as yogurt, kefir, sauerkraut, kimchee, and some cheeses, probiotic supplements can supply the body with many helpful microorganisms regularly.

Scientists have identified many probiotic species and strains that can support a healthy gut microbiome and immune function. Among them are Lactobacillus gasseri KS-13, which can support gastrointestinal function and immune health; Bifidobacteriuim bifidum G9-1, which may enhance immunity by reducing inflammation; and Bifidobacterium longum, which works to regulate bowel movements. All three of these probiotics can be found in Kyo-Dophilus® Daily Probiotic. Daily use of this probiotic may help promote better immune function.

Bottom line

Are you looking for ways to enhance and support your immune function for yourself and your family? Are you searching for safe, effective ways to achieve these goals? Along with a healthy diet, regular exercise, stress reduction, and being watchful of exposure to immune system-busting compounds like sugar, alcohol, and processed foods, consider the power of three: the addition of supplements that provide greens, aged garlic extract, and selected probiotics can help complete the picture.

Sources

12 powerhouse vegetables you should be eating. WebMD 2022 Aug 27

Gregor M. Greens. Nutrition Facts

Kim JH et al. Immunomodulatory functional foods and their molecular mechanisms. Experimental and Molecular Medicine 2022 Jan; 54(1):1-11.

Kwak JH et al. Beneficial immunostimulatory effect of short-term Chlorella supplementation: enhancement of natural killer cell activity and early inflammatory response (randomized, double-blinded, placebo-controlled trial). Nutrition Journal 2012 Jul 31; 11:53.

Mazziotta C et al. Probiotics mechanism of action on immune cells and beneficial effects on human health. Cells 2023 Jan 2; 12(1):184.

Percival SS. Aged garlic extract modifies human immunity. Journal of Nutrition 2016 Feb; 146(2):433S-436S.

Wu Q et al. The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview. Archives of Toxicology 2016 Aug; 90(8):1817-40

Xavier AA, Pérez-Gálvez A. Carotenoids as a source of antioxidants in the diet. Subcellular Biochemistry 2016; 79:359-75.

Xu C et al. Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial. Clinical Nutrition ESPEN 2018 Apr; 24:148-55.

The post Tune Up Your Immune System with the Power of Three appeared first on NaturallySavvy.com.

The need for better oral health care is considerable. A 2019 report from the Centers for Disease Control and Prevention notes that 26 percent of adults in the United States have tooth decay that has not been treated. Among adults aged 30 years and older, 46 percent have signs of gum disease. In Canada, the news is better. Eighty-four percent of Canadians say their dental health is good or excellent. However, good oral health requires a commitment to daily care.

In this article, we will explore using aloe vera to manage dental care and maintain oral health.

What is aloe vera?

Aloe vera, or Aloe barbadenis miller, is a succulent with fleshy, serrated leaves found primarily in dry areas of the world, including parts of Africa, Europe, the Americas, India, and Asia. The leaves are made up of three layers:

• the rind (outer layer) that protects the plant and also makes proteins and carbs;
• a middle layer composed of a bitter sap called latex, as well as substances called anthraquinones and glycosides;
• The inner layer is formed nearly entirely of water, amino acids, lipids, vitamins, sterols, and glucomannanas.

What’s unique about aloe vera?

Approximately 75 active substances can be found in aloe vera. Some properties make it a good candidate for helping manage oral health.

• Vitamins A and C are potent antioxidants. Vitamin A helps keep mucus membranes healthy and thus aids in preventing dry mouth. Vitamin C is involved in collagen production and contributes to connective tissue health.
• Enzymes, especially bradykinesia, can help reduce inflammation when applied topically.
• Calcium, magnesium, and zinc minerals are essential for strong teeth.
• Polysaccharides, including acemannan (aka glucomammose), have demonstrated an ability to aid in mineralization and dentin formation and thus strengthen teeth.
• Plant steroids, including cholesterol, campesterol B-sitosterol, and lupeol. These have anti-inflammatory abilities, and lupeol also provides pain-reducing properties.
• Other substances in aloe vera that may contribute to better oral health include saponins, which have antiseptic properties, and salicylic acid, which has antibacterial and anti-inflammatory abilities.

Oral health issues

The most common complaints people have concerning their oral health are:

• Cavities: Also known as caries or tooth decay, they are tiny holes in the hard surface of the teeth.
• Gingivitis: Accumulation of plaque on the teeth. Too much plaque can result in inflamed, painful, and bleeding gums.
• Periodontitis (gum disease): Develops when gingivitis is not treated. This gum disease destroys the bone that supports teeth and causes bad breath and receding gums.
• Bad breath: Foul-smelling breath that can occur because of dehydration, poor dental hygiene, and eating certain foods.
• Mouth ulcers: Small sores that develop on the lips, tongue, and other areas inside the mouth. They can be caused by factors such as biting your tongue or cheek, wearing braces, using abrasive toothpaste, eating acidic foods, hormonal fluctuations, and stress.

Poor oral health can tremendously impact your overall physical and emotional health. The University of Illinois Chicago School of Dentistry has reported on an association between periodontitis and the development of Alzheimer’s disease, prediabetes, type 2 diabetes, and obesity.

Poor dental health also has been associated with cardiovascular disease risk, according to a Harvard report. One reason may be that infections of the gums may reach the blood vessels and cause inflammation and damage that results in clots, strokes, or heart attacks. The Harvard report also mentions a connection between poor oral health, rheumatoid arthritis, and pancreatic cancer.

Aloe vera and oral health: research

The anti-inflammatory, antibacterial, and antioxidant properties of aloe vera have prompted people to use it to manage various dental problems. For example, in one study, 45 individuals with gingivitis were asked to rinse with aloe vera mouthwash alone, undergo scaling, or use the aloe vera mouthwash and have scaling. All the patients showed an improvement in gingivitis, but those in the aloe vera and scaling group had the most reduction. In a study of people with periodontitis, using aloe vera gel with scaling and root planing resulted in a better outcome than scaling and root planing alone.

The use of aloe vera also can destroy Streptococcus mutans, bacteria that produce plaque. In a 2019 study, researchers found aloe vera helped inhibit S. mutans growth.

In other research, patients with oral submucous fibrosis were treated with either aloe vera juice or aloe vera gel for three months or hydrocortisone and hyaluronidase for six weeks and antioxidants for three months. The effectiveness of the aloe vera was comparable to that of the other treatment. Experts also have shown that aloe vera gel is effective in speeding up healing from mouth ulcers and also reduces pain and wound size.

Using aloe vera for oral health

You can use aloe vera to support your dental health by using commercial toothpaste and mouthwash that contain the gel, or you can make your own products. Whether you buy products that already have aloe vera or you make your own, buy aloe vera that is all-natural and organic.

Mix 1 to 2 tablespoons of natural aloe vera gel and a drop of cinnamon, lemon, orange, or peppermint essential oil to make your toothpaste. Place a small amount on your toothbrush. Store the excess in a glass airtight container.

Homemade aloe vera mouthwash requires a few more ingredients. You will need a clean, empty glass jar with a lid.

• ½ cup aloe vera juice
• ½ cup distilled water
• 1 ½ tsp baking soda

Combine the ingredients in the bottle, put on the lid, and shake well until everything has dissolved. Refrigerate the unused mouthwash. To use, swish a small amount in your mouth for 20 seconds, then gargle for a few seconds before spitting out the mouthwash. Do not swallow the mouthwash. If you don’t like the taste, add 1 to 2 drops of peppermint, orange, lemon, or peppermint essential oil.

Oral use of aloe vera gel and juice is generally safe, but some people experience allergic reactions. A 2019 study reported that “topical and oral use of Aloe vera can cause skin irritation, hives, cramping, and diarrhea to those allergic to other plants in the lily family…onion and tulips.” Before using aloe vera, a patch test is recommended. If you experience any reactions, stop using aloe vera immediately. Never use aloe latex orally, as it can cause stomach cramps and irritation. Children and pregnant and breastfeeding women should always check with their physician before using aloe vera.

Other ways to use aloe vera

Aloe vera is also used to help manage other health concerns, including skin irritation and dryness, sunburn, diabetes (which may help lower blood sugar), and digestive issues such as indigestion, constipation, and heartburn (aloe vera juice). Talk to your healthcare provider about how aloe vera may be effective for other symptoms and health concerns.

Bottom line

Aloe vera is a natural, complementary remedy with antibacterial, anti-inflammatory, and antioxidant properties that may prove helpful in the management of oral health issues. Along with regular checkups, daily oral care, and teeth cleanings, aloe vera can be a part of your oral care routine.

[Editor's Note: We trust the brand Lily of the Desert for our aloe vera. We've been using it for years for everything from boo-boos to digestion. Learn more about it on their site.]

Sources

Ajmera N et al. Aloe vera: It's effect on gingivitis. Journal of Indian Society of Periodontology 2013 Jul; 17(4):435-38.

Anuradha A et al. Evaluation of efficacy of aloe vera in the treatment of oral submucous fibrosis – a clinical study. Journal of Oral Pathology & Medicine 2017 Jan; 46(1):50-55.

Babaee N et al. Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis. Dental Research Journal (Isfahan) 2012 Jul; 9(4):381-85.

Centers for Disease Control and Prevention. Oral Health Surveillance Report: Trends in Dental Caries and Sealants, Tooth Retention, and Edentulism, United States, 1999–2004 to 2011–2016. Atlanta, GA: Centers for Disease Control and Prevention, US Dept of Health and Human Services; 2019.

Curatola G. 9 vitamins and minerals for healthy teeth. Rejuvenation Dentistry 2023 Jan 30

DIY homemade mouthwash recipes you can easily make. Soundview Family Dental. 2020 Oct 18

Eke P et al. Periodontitis in US adults: National Health and Nutrition Examination Survey 2009-2014. JADA 2018; 149(7):576-86.

Fallahi HR et al. Effect of aloe vera mouthwash on postoperative complications after impacted third molar surgery: a randomized, double-blind clinical trial. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 2016 Sep 5; 28(5):392-96

Guo X, Mei N. Aloe vera: a review of toxicity and adverse clinical effects. Journal of Environmental Science and Health, Part C. Environmental Carcinogenesis and Ecotoxicology Reviews. 2016 Apr 2; 34(2):77-96

Higuera V. Benefits of aloe vera for your gums. Healthline 2019 Aug 14

Mangaiyarkarasi SP et al. Benefits of Aloe vera in dentistry. Journal of Pharmacy and Bioallied Sciences 2015 Apr; 7(Suppl 1):S255-59.

Sánchez M et al. Pharmacological update properties of Aloe Vera and its major active constituents. Molecules 2020 Mar 13; 25(6):1324.

Shmerling RH. Gum disease and the connection to heart disease. Harvard 2021 Apr 22

Sholehvar F et al. The effect of Aloe vera gel on viability of dental pulp stem cells. Dental Traumatology 2016 Oct; 32(5):390-96.

Sultan MS. Antibacterial effect of aloe vera and glass ionomer modified by aloe vera on Streptococcus mutans. Egyptian Dental Journal 2019 Jul; 65(3):2607-16

The surprising connections between dental health and well-being. University of Illinois Chicago School of Dentistry 2019 Jan 14

The state of oral health in Canada. Canadian Dental Association.  2017 Mar

Surjushe A et al. Aloe vera: a short review. Indian Journal of Dermatology 2008; 53(4):163-66.

The post Aloe Vera and Oral Health appeared first on NaturallySavvy.com.

However, even though – according to the CDC –  over 5 million Americans were suffering from this, it’s not usual to see early onset Alzheimer’s. Early-onset Alzheimer's affects people between 40 and 50 years old.

This progressive illness affects memory and leads to difficulty with communication and social interactions.

The challenge in the early stages is obtaining an accurate diagnosis due to many symptoms being caused by things like stress, anxiety, certain medications, thyroid problems, sleep disorders, nutritional deficiencies, etc.

A great example is stressful situations in your daily life. During these times, it’s normal to forget one or two things.

However, if you think you could have early symptoms of dementia, this article with seven signs of early-onset Alzheimer’s will help you recognize them.

Causes For Early-Onset Alzheimer's Disease

The thing about Alzheimer’s is that there are still a lot of unanswered questions about how it develops. Some proteins appear in the brain that are linked with Alzheimer's development. Two specific types of proteins are often associated with the condition: beta-amyloid proteins and tau proteins. What these proteins do is disrupt normal cellular and molecular processes and attack the areas of the brain associated with memory.

This affects daily activities and behavior.

Some genes can increase the risk of developing early-onset Alzheimer's. These include:

• APOE (Apolipoprotein E) Gene, especially the APOE E4 gene
• PSEN1 (Presenilin 1) and PSEN2 (Presenilin 2) Genes
• APP (Amyloid Precursor Protein) Gene

Risks For Early-Onset Alzheimer's Disease

The risk factors for developing early-onset Alzheimer's include:

• Genetics
• Family history
• Medical conditions like cardiovascular disease, diabetes, and head injuries.
• Environmental factors like exposure to toxins
• Lifestyle factors include a sedentary lifestyle, poor diet, smoking, and excessive alcohol consumption.

Can You Diagnose Early-Onset Alzheimer's Disease?

Diagnosing early-onset Alzheimer's involves a comprehensive evaluation by a healthcare professional, including a thorough medical history, physical examination, and various tests and assessments. The goal is to rule out other potential causes of cognitive impairment and to identify any underlying factors contributing to the symptoms. Here are some of the tests and assessments commonly used in diagnosing early-onset Alzheimer's disease:

• Neurological tests.
• Cognitive exercises.
• Neuropsychological Testing
• Blood samples.
• MRI, PET, or CTs.
• Cerebrospinal Fluid Analysis
• Genetic Testing
• Functional and Behavioral Assessments
• Family and Caregiver Interviews

7 Signs of Early-Onset Alzheimer's

Early-onset Alzheimer's is not easily detectable, but if you experience these symptoms, see a qualified healthcare professional to rule out other underlying causes.

Memory Loss

If you find yourself forgetting important things, such as special events, familiar faces that you should remember (like your mom's), or repeating questions, these could be signs pointing to memory loss.

You Have A Hard Time-Solving Problems or Planning

A person with real AD symptoms will have difficulty focusing on numbers and following or developing a plan. Struggling to follow directions or instructions, even simple ones, and needing frequent reminders.

You Can’t Finish Simple Tasks Correctly

You're having trouble focusing or maintaining attention on tasks, making it challenging to complete complex or multi-step activities like making a recipe you've made many times before.

You Can’t Find The Right Words

Experiencing difficulty in finding the right words during conversations or having frequent "tip-of-the-tongue" moments.

You Avoid Crowds And Social Events

People with AD find social events difficult. If you or someone you know is constantly rejecting going out because they feel uncomfortable when these social situations, it could be a sign of dementia.

Your Personality Changes Constantly

Changing behavior or personality could be related to bipolar disorder. However, it could also be an AD sign. Confusion, anxiety, fear, angry outbursts, or depression are common moods you could feel.

You Can’t Understand Images

Not recognizing images, especially familiar ones, can be a sign of cognitive impairment or a cognitive disorder like Alzheimer's disease.

Preventing Early-Onset Alzheimer's

Here are some lifestyle changes you can make to decrease your chances of developing early-onset Alzheimer's.

• Get regular exercise even if it's just a walk. Keeping active is very important to brain health.
• Practice great sleep hygiene. Our glymphatic system cleans our brains when we are sleeping. So having great sleep is so important.
• Eating healthier food.
• Training your cognitive skills.
• Keep learning new things. Try puzzles, pick up a new language, learn to play an instrument, or take dance classes.

Preparing for the Future

If you or a family member has been diagnosed with early-onset Alzheimer's be prepared for the future by putting things in place today.

For example:

• Buying life insurance.
• Modifying your house so you can age safely in place.
• Looking for professionals and caregivers to help.

The post 7 Signs of Early-Onset Alzheimer’s and What You Should Do appeared first on NaturallySavvy.com.

Today, many people turn to aloe vera to treat sunburn and other minor burns, scrapes, bruises, and cuts. Aloe vera plants are commonplace on kitchen windowsills and in home gardens. But have you ever thought about using aloe vera for blood sugar management? Yes, it’s been shown to improve blood glucose levels.

What is aloe vera?

Aloe vera is a succulent that is native to dry areas of America, Europe, Africa, and Asia. It’s composed of fleshy leaves, yellow flowers, and fruits with seeds. The leaves are made of three layers.

• The outer thick layer is the rind, which protects the plant and makes proteins and carbohydrates.
• The inner clear gel is 99 percent water and 1 percent beneficial substances.
• A middle layer is composed of latex that contains glycosides and anthraquinones, which have laxative effects.

Aloe vera contains about 75 potentially active ingredients, including vitamins, sugars, lignin, saponins, salicylic acids, amino acids (20 of the 22 required amino acids), enzymes, and minerals.

Read about 9 reasons to use aloe vera juice every day

In addition to using the inner gel of the plant directly on the skin, aloe vera is used in many different products, such as creams and lotions for topical use, as well as aloe vera juice for internal conditions such as indigestion, heartburn, and other digestive issues.

Aloe vera and blood glucose levels: studies

Another potential use for aloe vera juice is to help improve blood glucose (sugar) levels. In a 1999 study, researchers indicated that oral aloe vera “might be a useful adjunct for lowering blood glucose in diabetic patients.” Since then, experts have continued to explore aloe vera's use in managing blood glucose and diabetes. Thus far, some of their findings include the following:

• In a study involving 90 individuals with non-insulin-dependent diabetes, the participants were given either no treatment (controls), 100 mg of aloe vera gel powder, or 200 mg of the powder daily for 3 months. The authors noted a significant drop in fasting blood glucose levels and post-prandial glucose levels in the groups that received aloe vera but not in the controls. The participants in the aloe vera groups also saw a significant reduction in total cholesterol, triglycerides, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol, and a significant increase in high-density lipoprotein cholesterol. Blood pressure declined significantly in the aloe vera groups but only slightly in the controls.
• In a 2013 animal study, aloe vera extract was administered to diabetic rats. The extract significantly reduced glucose levels while also significantly increasing serum insulin levels.
• In a systemic review and meta-analysis that involved eight trials (470 patients) with prediabetes or type 2 diabetes, the researchers found that the use of aloe vera significantly improved fasting plasma glucose levels in people with prediabetes. For those with type 2 diabetes, aloe vera may improve glycemic control and significantly improve hemoglobin A1c levels.
• A 2022 study looked at the impact of aloe vera on dyslipidemia (elevated triglycerides, decreased high-density lipoprotein [good] cholesterol, elevated small dense low-density lipoprotein [bad] cholesterol) in individuals with type 2 diabetes. The authors noted that oral aloe vera may help improve blood glucose stability and the metabolism of lipids.

Read about why we love (and why you should love) aloe vera

The positive effects of aloe vera may be associated with the presence of various compounds. They include:

• Anthraquinones have anti-inflammatory and antioxidant properties.
• Acetylated mannan, also known as acemannan, which has anti-diabetic and anti-inflammatory properties.
• Aloe vera carbohydrate-rich fraction has been shown to regulate glucose metabolism in diabetic rats. In a 2021 study, the authors reported that the carbohydrate fraction of aloe vera improved glucose metabolism and helped maintain glucose homeostasis. They concluded that aloe vera carbohydrate-rich fraction “can be used as an alternative medicine to alleviate diabetes mellitus symptoms.”
• Glucomannan is a type of dietary fiber that may help lower blood glucose levels.

Using aloe vera

You can use aloe vera juice, gel, or supplements for blood sugar management. Choose an organic aloe vera product. A typical dose of aloe vera juice is one to three tablespoons daily.

Bottom line

Aloe vera is a natural supplement that may be used to help with blood glucose management in prediabetes and diabetes. However, consult a knowledgeable professional before using aloe vera because it may lower your blood glucose too much, especially if you already take diabetic medication.

[Editor's Note: Lily of the Desert grows and harvests aloe vera plants in the United States to provide a full line of aloe vera juices to choose from. Learn more at Lilyofthedesert.com.]

Sources

Abo-Youssef AMH, Messiha BAS. Beneficial effects of Aloe vera in treatment of diabetes: comparative in vivo and in vitro studies. Bulletin of Faculty of Pharmacy, Cairo University 2013 Jun; 51(1):7-11

Choudhary M et al. Hypoglycemic and hypolipidemic effect of Aloe vera L. in non-insulin dependent diabetics. Journal of Food Science and Technology 2014 Jan; 51(1):90-96

Deora N, Venkatraman K. Aloe vera in diabetic dyslipidemia: Improving blood glucose and lipoprotein levels in pre-clinical and clinical studies. Journal of Ayurveda and Integrative Medicine 2022 Oct-Dec; 13(4):100675

Govindarajan S et al. Aloe vera carbohydrates regulate glucose metabolism through improved glycogen synthesis and downregulation of hepatic gluconeogenesis in diabetic rats. Journal of Ethnopharmacology 2021 Dec 5; 281:114556.

Shelton RM. Aloe vera. Its chemical and therapeutic properties. International Journal of Dermatology  1991 Oct; 30(10):679-83

Suksomboon N et al. Effect of Aloe vera on glycaemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis. Journal of Clinical Pharmacy and Therapeutics 2016 Apr; 41(2):180-88.

Surjushe A et al. Aloe vera: a short review. Indian Journal of Dermatology 2008; 53(4):163-66.

Yongchaiyudha S et al. Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus. Phytomedicine 1996 Nov; 3(3):241-43.

Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. British Journal of General Practice 1999 Oct; 49(447):823-28

The post Aloe Vera – Effects on Blood Glucose and Benefits appeared first on NaturallySavvy.com.

What is glaucoma and diabetic retinopathy?

Glaucoma is a condition where there is increased pressure in the eye leading to damage of the optic nerve and vision loss. A person with diabetes is almost twice as likely to get glaucoma. Diabetic retinopathy is when damage to the blood vessels in the retina occurs. Both conditions can occur with few warning signs until it is quite advanced. Both of these conditions ultimately can lead to complete blindness. That is why regular eye exams and preventative measures are so important in keeping your eyes healthy.

Why are diabetics more prone to eye problems?

Diabetes is the leading cause of blindness in adults. Elevated sugar levels in the bloodstream can cause damage to the cells in your eyes. Having excess sugar flowing through your bloodstream can act like small shards of glass to your blood vessels. In helping to prevent this, doing what you can to lower your sugar levels and manage your diabetes is extremely important.

What can you do to protect yourself from eye problems?

• Keep good control of your blood sugar levels. This is the single most important preventative step anyone with diabetes can do. Not only will proper monitoring of blood sugar levels reduce your risk of eye diseases but it can also prevent a variety of other complications from occurring as well.

• See an Ophthalmologist (an eye doctor who specializes in eye diseases) or Optometrist for regular checkups including dilated eye exams at least once a year. Early detection is important in helping to reduce further damage to your eyes. If you detect any changes to your sight, consult an eye doctor immediately.

• Keep your blood pressure in a normal range. High blood pressure along with elevated cholesterol levels play a crucial role in the maintenance of eye health.

• Eat a balanced diet with a wide variety of vitamins and minerals. One of the easier ways to do this is to consume foods with a variety of colors. This will also help keep your blood sugar levels in check. Maintaining a balanced diet is one of the easiest ways to ensure good overall health.

Taking the time and effort to manage your diabetes and keeping your blood sugar levels in check is important in reducing your risk of suffering from complications. Making the changes now could also reduce your risk of eye problems in the future. Do yourself a favor and start making these positive changes today, and your eyes will ultimately thank you in the long run.

Susanna Deering has a passion for nutrition and great-tasting food. As a type 1 diabetic, Susanna is deeply aware firsthand how important the right foods are to our diets. Learning to live with diabetes grew Susanna’s passion for nutrition and has inspired her to help others manage their health through nutrition as well.

The post The Importance Of Eye Care For Diabetics appeared first on NaturallySavvy.com.

What is aloe vera?

You may be most familiar with aloe vera as a natural remedy for sunburn and minor skin burns, as well as minor cuts and scrapes. Many people like to keep an aloe vera plant in the kitchen or close by to handle such medical issues.

Aloe vera is a succulent plant that grows in tropic, subtropical, and arid areas of the world. It is well known for its anti-inflammatory, antibacterial, and antioxidant properties. In addition to the skin-related conditions already mentions, it is widely used both topically and internally for moisturizing and hydrating the skin, digestive problems, constipation, arthritic swelling, gum infections, and more.

Read about 16 reasons why aloe vera rocks

Aloe vera for acne: topical

The antibacterial, antioxidant, and anti-inflammatory properties of aloe vera gel and cream make them effective tools for fighting acne. You can apply pure aloe vera gel or cream on the skin to help prevent acne breakouts and to help eliminate bacteria that promote the development of more papules. Aloe vera can be applied to existing acne and left on overnight and then washed off with warm water in the morning.

Aloe vera is very mild on the skin and typically poses little to no risk. However, you should always do a small test patch or consult with a dermatologist before applying aloe vera or any other substance for the first time on your face.

You may want to try an aloe vera face mask for acne:

Aloe vera, cinnamon, and honey: All three of these ingredients have antibacterial properties, so combining them may create a potent face mask. To make the mask, combine 2 tablespoons of pure honey and 1 tablespoon of pure aloe vera until it is easy to spread. Add ¼ tablespoon of ground cinnamon and mix well. Apply the mask to your face and allow it to stay on for 5 to 10 minutes. Rinse with warm water thoroughly.

Aloe vera and lemon juice: This combination will both refresh your skin while also cleaning the pores and killing bacteria. Lemon juice has exfoliative properties that can be helpful in fighting acne. For this mask, combine 2 tablespoons of pure aloe vera with ¼ teaspoon of lemon juice. Leave the mixture on your face for 5 to 10 minutes and then rinse it off completely with warm water. Because lemon juice can be irritating, you can reduce the amount of lemon juice if you notice some discomfort.

Aloe vera gel also can help with healing wounds and scars. The vitamins, minerals, enzymes, amino acids, and other antibacterial and anti-inflammatory agents in the gel can increase collagen in the skin, lessen inflammation, promote the skin’s elasticity, and heal wounds. Experts have found that aloe vera can help treat wounds, prevent skin ulcers, and retain skin moisture and integrity.

Several new studies have looked at using aloe vera in addition to other methods to treat acne. A 2021 study explored the use of topical aloe vera gel and soft mask along with ultrasound, which enhances the absorption of aloe vera gel. The participants had mild to severe acne and were divided into two groups: treatment and controls. Individuals in the treatment group experienced a significant reduction in the number of acne papules and hyperpigmented lesions as well as showed an improvement in skin roughness and facial blood circulation. Participants in the control group did not show these benefits.

A more recent study (2023) used a combination of aloe vera (Aloe barbadensis) and mung beans (Vigna radiata) to treat acne. The author reported that the mixture showed “a promising effect on acne together with an additive effect of Aloe barbadensis on skin.”

Read about 9 reasons to use aloe vera juice every day

Aloe vera for acne: internal

You can also help protect your skin against acne by taking aloe vera juice. This slightly gooey liquid contains polyphenols, which have antioxidant properties that can help support immune function and enhance gut health and in turn may contribute to skin health. Divya Jacob, Pharm.D. notes that drinking aloe vera juice can help reduce the frequency and severity of acne.

One study, for example, found that components of aloe vera juice can help stimulate the production of collagen and hyaluronic acid and thus support skin health. Use aloe vera juice according to package directions or consult with a knowledgeable healthcare professional.

Bottom line

Aloe vera used either topically or internally can benefit skin health and help manage acne. Before consuming aloe vera juice, talk to your doctor if you have any health conditions such as heart disease, diabetes, kidney disease, hepatitis, or other health concerns.

[Editor's Note: Lily of the Desert is a quality brand of aloe vera, grown in the US. You can check out their online store or find their products at your local health food store.]

Sources

Chavan D. Aloe vera for acne scars: miracle cure or old wives tale. Clearskin 2021 Jun 30

Chellathurai BJ et al. Development of a polyherbal topical gel for the treatment of acne. Gels 2023 Feb 17; 9(2):163.

Fletcher J. Can aloe vera help with acne? Medical News Today 2018 Mar 21

Hekmatpou D et al. The effect of aloe vera clinical trials on prevention and healing of skin wound: A systematic review. Iranian Journal of Medical Sciences 2019 Jan; 44(1):1-9.

Jacob D. Is it good to drink aloe vera juice every day? MedicineNet 2022 May 9

Landes E. 5 healthy benefits of drinking aloe vera juice. Healthline 2023 Feb 23

Rahmani AH et al. Aloe vera: Potential candidate in health management via modulation of biological activities. Pharmacognosy Reviews 2015 Jul-Dec; 9(18):120-26.

Shenefelt PD. Chapter 18. Herbal treatment for dermatological disorders. In Herbal Medicine Biomolecular and Clinical Aspects. 2^nd edition.

Tanaka M et al. Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women. Clinical, Cosmetic, and Investigational Dermatology 2015 Feb 20; 8:95-104. 

Watson K. How to use aloe vera for acne. Healthline 2019 Mar 8

Zhong H et al. Efficacy of a new non-drug acne therapy: Aloe vera gel combined with ultrasound and soft mask for the treatment of mild to severe facial acne. Frontiers in Medicine (Lausanne) 2021 May 21; 8:662640.

The post Aloe Vera and Acne appeared first on NaturallySavvy.com.

Before you randomly choose a supplement that claims to help with cognition and brain health, it’s a good idea to better understand how your brain works and what some natural ingredients can do for your brain.

How the brain works

The human brain goes through incredible changes over time. Memory, perception, and emotions are being developed from birth to age six years, and wiring of neurons (brain cells) continues until the middle to late 20s, when brain maturity peaks. However, that doesn’t mean it’s all downhill from there!

Read about better brain health for students and seniors

Research in Cell Stem Cell has shown that new brain cells don’t decline with age and in fact continue to be produced with age. People can still learn new skills until the day they die. At the same time, changes occur in the brain as we age. For example:

• The brain generates fewer chemical messengers such as dopamine, serotonin, and other neurotransmitters as it ages. This can have a role in waning memory and cognition as well as a greater risk of depression.
• Both the frontal lobe and hippocampus of the brain undergo shrinkage around age 60. These areas of the brain are involved in memory, emotions, and learning.
• The white matter in the brain is composed of bundled nerve fibers that serve as a roadway for nerve signals between neurons. The protective covering (myelin) on nerve cells shrinks as we age, which in turn slows the processing of the signals and reduces cognitive function.
• Synaptic connections (the direct electrical and chemical connections between nerve cells) decline, resulting in thinning of the brain along the outer ridged surface. This can contribute to slower cognitive processing.

Supplements for better brain health

Several substances have been shown to support and boost cognitive function and brain health. Each one has specific benefits, so when shopping for a brain health supplements, you can choose products that have the combination of benefits you want.

• Ginkgo biloba is a large tree that is considered to be a living fossil because it is the oldest living tree. It has a long history of aiding memory and blood disorders and in improving circulation. A research team that reviewed lots of data on the benefits of ginkgo biloba reports that it “shows promise in patients with dementia, normal aging, and cerebrovascular-related disorders,” and help with memory and processing of information. Other research has shown that ginkgo biloba has an ability to improve recognition, short- and long-term recall, and spatial working memory. [Wakunaga Brain Focus Supplement is a great source of ginkgo biloba.]
• Eleuthero ginseng extract is also sometimes referred to as Siberian ginseng. It was first used in China about two millennia ago and is valued as an antioxidant and immune system helper. Study result indicate that eleuthero ginseng may improve memory and provide neuroprotective effects. By increasing blood circulation, the extract may boost blood flow to the brain and thus enhance memory and cognition. [Try Brain Memory Supplement for Wakunaga for eleuthero ginseng.]
• Aged garlic extract begins as ordinary garlic that is then aged using a special process that eliminates odor-causing compounds while also boosting the bioavailability of the garlic’s beneficial ingredients. According to a recent review in Experimental and Therapeutic Medicine, aged garlic extract is beneficial against learning and cognitive memory deficits.

Read about aged garlic extract, AGE for a healthier you

• Choline is a nutrient made in the liver and similar to B vitamins. It plays various roles in the nervous system and brain functioning. Eggs, nuts, beans, meat, fish, and vegetables all are sources of choline (as lecithin, the main source of choline in food). A 2023 report has shown that choline supplements are effective in enhancing cognitive function and memory.
• Carnitine is a substance that is made in the brain, liver, and kidneys and helps the body turn fat into energy. Some research has indicated that this amino acid derivative may be useful in some individuals who have Alzheimer’s disease or other dementia, although more research is needed.
• Phosphyatidylserine is a fatty substance that protects brain cells and transports signals between them. Therefore, it plays a critical role in maintaining brain health and memory. Researchers have concluded that phosphatidylserine is necessary for healthy brain cell membranes and cognitive functioning, including short-term and long-term memory, the creation of new memories, the ability to retrieve memory, as well as the ability to focus, concentrate, pay attention, reason, solve problems, learn and recall information, and communicate.
• Folic acid is a B vitamin often associated with helping prevent birth defects, but it also has a significant role in brain health and memory. Researchers involved in a 2022 systematic review and meta-analysis found that among individuals 70 years and older treated for six months or longer, folic acid supplementation had a significant favorable impact on memory when taking 6 to 11 milligrams daily and a significant decline when taking 17 to 20 milligrams daily. Experts also point out that folic acid (and the natural form, folate, found in food) must be metabolized into L-methylfolate so it can cross into the brain and help with production of dopamine, serotonin, and norepinephrine, which contribute to mental function.

How to enhance brain health with lifestyle

In addition to supplementation, there are other things you can do to enhance your brain health.

• Choose healthy foods. The Mediterranean and DASH diets are two examples of dietary approaches that have been shown to be wise choices for brain health and reducing cognitive decline. Both focus on fruits and vegetables, monounsaturated fats, whole grains, fish, nuts, and seeds while minimizing red meat and avoiding processed foods.
• Get lots of Zzzzzx. Adults need 7 to 9 hours of sleep nightly. During sleep, the brain saves new information and also improves memory retention. Getting high-quality sleep supports problem-solving, creativity, emotional processing and judgment, attention, and concentration.
• Move regularly. Daily exercise, especially aerobic activities such as walking, pickleball, dancing, and biking, can help improve memory in adults 55 and older.
• Exercise your brain. Make it a point to learn new skills, whether it’s a language or an instrument, artistic project, or mind-challenging games. Cognitive games that can help you improve working memory, verbal memory, thinking speed, and problem-solving skills are available online. Search for brain training programs.
• Be social. Stay in touch with family, friends, neighbors, and coworkers. If you find yourself becoming isolated, join clubs or groups that share your interests or new hobbies. Many are also available virtually online if in-person meetings are challenging.
• Take supplements. High-quality supplements that contain one or more of the brain-supporting substances discussed here are a way to enhance your brain health.

Bottom line

Brain health, memory retention, and overall cognitive function can be maintained and improved by adopting healthy lifestyle habits and supporting them with supplements.

[Wakunaga has many of these ingredients in their supplements including their Neuro-Logic and their Stress and Fatigue Formulas.]

Sources

Aghjayan SL. Aerobic exercise improves episodic memory in late adulthood: a systematic review and meta-analysis. Communications in Medicine 2022; 2(15).

Akhgarjand C et al. Does folic acid supplementation have a positive effect on improving memory? A systematic review and meta-analysis of randomized controlled trials. Frontiers in Aging Neuroscience 2022 Nov 28; 14:966933.

Boldrini M et al. Human hippocampal neurogenesis persists throughout aging. Cell Stem Cell 2018 Apr 5; 22(4): 589-99

Carnitine. National Institutes of Health. 2023 Apr 17

Columbia University. Changes that occur to the aging brain: what happens when we get older. 2021 Jun 10

Diamond BJ et al. Ginkgo biloba extract: mechanisms and clinical indications. Archives of Physical Medicine and Rehabilitation 2000 May; 81(5):668-78.

Ginkgo biloba. Mount Sinai.

Glade MJ, Smith K. Phosphatidylserine and the human brain. Nutrition 2015 Jun; 31(6):781-86.

Huizen J. 12 potential health benefits of aleuthero. Medical News Today 2017 Aug 23

Kansakar U et al. Choline supplements: An update. Frontiers in Endocrinology (Lausanne). 2023 Mar 7; 14:1148166.

Leahy LG. Vitamin B Supplementation: What's the right choice for your patients? Journal of Psychosocial Nursing and Mental Health Services 2017; 55:7–11.

Román GC et al. Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease. Revue Neurologique (Paris) 2019 Dec; 175(10):724-41.

Sripanidkulchai B. Benefits of aged garlic extract on Alzheimer's disease: Possible mechanisms of action. Experimenal and Therapeutic Medicine 2020 Feb; 19(2):1560-64.

Tomova T. An experimental study on phytochemical composition and memory enhancing effect of Ginkgo biloba seed extract. Folia Medica 2021; 63(2):203–12.

The post Building Better Brain Health Naturally appeared first on NaturallySavvy.com.

Despite the new designation by the IARC for aspartame, the Food and Drug Administration (FDA) stated on July 14, 2023, that it “disagrees with IARC’s conclusion” that the studies they evaluated “support classifying aspartame as a possible carcinogen to humans.” The FDA maintains that the IARC’s review has “significant shortcomings in the studies on which IARC relied.”

The FDA also noted that WHO and many other countries consider aspartame to be safe “at current permitted use levels.” Those levels (Acceptable Daily Intake, or ADI) is 40 milligrams/kilogram of body weight, approved by Health Canada and the European Food Safety Authority.

Read about aspartame and anxiety: cruel connection

To put it into perspective, an adult weighing 184 pounds (83 kilograms) would reach that limit when consuming about 33 cans of a diet soft drink in one day. In the US, individuals could drink even more diet soft drinks (40 cans) to reach the limit, as the ADI is even greater: 50 milligrams/kilogram of body weight.

What is aspartame?

This artificial sweetener, which was approved by the US Food and Drug Administration in 1981, is known in scientific circles as L-aspartyl-L-phenylalanine methyl ester. It is composed of two amino acids, aspartic acid and phenylalanine, and is about 200 times sweeter than table sugar. It is used in many diet beverages, no- and low-calorie gums and candies, low-calories ice cream and other desserts, and other food items. Aspartame is also available in packets to be used in coffee, tea, and is added to foods such as cereals and smoothies.

How harmful is aspartame?

Studies over the past decades have found aspartame to be a health concern in animal and human studies. In a 2021 study entitled “Aspartame and cancer—new evidence for causation,” the authors conducted an immunohistochemical and morphological re-evaluation of original animal research and aspartame. Their findings confirmed that aspartame is a carcinogen in rodents and that prenatal exposure to the chemical increases cancer risk in rodent offspring. The authors “encourage all national and international public health agencies to urgently reexamine their assessments of aspartame’s health risks” and for “food agencies to reassess Acceptable Daily Intake” levels for aspartame.

In a later study, nearly 103,000 individuals participated in an analysis of their use of artificial sweeteners. The authors found that compared with nonconsumers, those who had higher intake of artificial sweeteners (especially aspartame and acesulfame-K) had a greater risk of overall cancer. Higher risks were seen for breast cancer and obesity-related cancers.

Read about the dangers of aspartame poisoning

Homer Swei, the Environmental Working Group’s senior vice president, Healthy Living Science, stated that “For years we’ve known that artificial sweeteners like aspartame are harmful to human health,” noting a rise in type 2 diabetes and obesity as well as a greater risk of cardiovascular disease. “We suspected aspartame might be a carcinogen as well, but this determination unequivocally solidifies that concern.” He emphasized that the FDA “should take seriously these latest troubling findings, which could put consumers, particularly children, at greater risk of cancer.”

According to Dr. Francesco Branca, director of WHO’s Department of Nutrition and Food Safety and who was part of the team that performed risk evaluation of aspartame, consumers have three choices when it comes to choosing sodas. They can select one with sugar, one with artificial sweeteners, or reach for water. He emphasized that it’s important for everyone to limit the amount of sweet beverages and foods they consume, regardless of whether they contain real or artificial sugar.

Bottom line

For years, some experts have noted that aspartame is associated with significant health risks. The new designation of possible carcinogen for aspartame by WHO’s International Agency for Research on Cancer has not changed the consumption guidelines but it has highlighted the health concerns noted with use of this artificial sweetener. As noted by Dr. Thomas Galligan, principal scientist for food additives and supplements with the Center for Science in the Public Interest, the declaration by WHO should “raise alarm bells for consumers.”

Sources

Aspartame. European Food Safety Authority 2023 Jun 28

Aspartame. Health Canada

Aspartame and other sweeteners in food. Food and Drug Administration 2023 Jul 14

Aspartame hazard and risk assessment results released. World Health Organization 2023 Jul 14

Christensen J. WHO declares widely used sweetener aspartame a possible cancer cause, but intake guidelines stay the same. CNN 2023 Jul 14

Debras C et al. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study. PLoS Medicine 2022 Mar 24; 19(3):e1003950.

Landrigan PJ, Straif K. Aspartame and cancer – new evidence for causation. Environmental Health 2021 Apr 12; 20(1):42.

The post WHO Declares Aspartame a Possible Carcinogen appeared first on NaturallySavvy.com.